กรุงเทพ & พิษณุโลก นิติธรรมคลินิก
Dull, dry, dehydrated skin, or the early signs of fine lines are usually not caused by a single-layer issue. They are often related to both the degradation of collagen in the dermis and the simultaneous loss of moisture in the Extracellular Matrix. DuoMatrix™ Skin Program by Nititham Clinic Designed to care for both dimensions of the skin in the same treatment plan. Book your appointment now via LINE: @nititamclinic
This program combines two complementary components.
Prepared from the patient’s own blood, it undergoes a centrifugation process to obtain platelet-rich plasma. Growth Factors in the platelets are involved in the tissue repair process, Fibroblast function, and the formation of skin components in the dermis.
Clinical evidence of PRP for facial skin rejuvenation shows a positive trend for skin quality and texture. However, results may vary, as the PRP preparation method, platelet concentration, injection technique, and number of treatment sessions across different studies are not yet standardized.
Non-crosslinked hyaluronic acid, unlike typical firm gel fillers, disperses well within the skin. It focuses on water retention and increasing moisture in the deep skin layers, while supporting the Extracellular Matrix environment, which is essential for skin cell function.
Both address three main goals, which include:
Biostimulation
Stimulating the skin's natural repair process from within
Hydration
Replenishes moisture in the deep skin layers
ECM Support
Supports the skin's structural framework
Standard PRP programs primarily focus on using platelet-rich plasma to support repair and stimulate the skin’s collagen production process.
The DuoMatrix™ program incorporates Non-Crosslinked HA into the treatment plan, providing comprehensive three-dimensional care simultaneously. This includes Biostimulation to stimulate internal repair mechanisms, Hydration to add moisture to the deep skin layers, and ECM Support to reinforce the structural framework of skin cells—aspects that a standalone PRP program does not directly address.
The Non-Crosslinked HA in this program is not designed to add volume or reshape the face like traditional dermal fillers. Its primary goal is to improve skin hydration and overall skin quality. For those looking to correct deep wrinkles, augment the chin, plump the lips, or reshape facial contours, the doctor will recommend a more suitable program during the assessment.
Skin that feels tight, dry, has trouble holding makeup, or looks dehydrated despite regular use of skincare products.
Skin that looks fatigued, lacks radiance, or has an uneven tone due to accumulated stress, insufficient rest, or age-related decline in skin quality.
Fine lines on the cheeks, around the eyes, neck, or back of the hands associated with dryness and loss of elasticity, including skin that is starting to thin or does not bounce back as well as before.
In cases where concerns are related to skin quality and diminished collagen structure
For individuals seeking to care for overall skin quality after experiencing dryness, sensitivity, or deterioration from external factors
Hydration from Non-Crosslinked HA is usually noticeable more quickly, while the effects of the PRP program related to the collagen production process will gradually develop depending on the body’s response. The skin may gradually show changes in the following areas:
The PRP program is not an instant filler. The rejuvenation process occurs gradually based on the body’s natural response, whereas hydration from HA may be noticeable sooner than collagen changes.
*Results may vary depending on age, skin condition, lifestyle, PRP quality, treatment technique, and the number of sessions.
The doctor assesses skin dryness, elasticity, wrinkles, texture, and specific concerns, while also reviewing your health history and current medications.
An appropriate amount of blood is drawn and processed through centrifugation to prepare platelet-rich plasma (PRP).
The doctor selects the appropriate product and dosage suited to the specific area, skin condition, and individual treatment plan.
The skin is cleansed, and appropriate pain management methods are applied depending on each specific area.
The doctor selects an injection technique tailored to the individual's skin condition and specific treatment area.
Patients will receive instructions on post-treatment skin care, avoiding heat exposure, and monitoring for any symptoms that require contacting the clinic.
The number of sessions depends on individual skin concerns and goals. The doctor may recommend a series of multiple treatments at appropriate intervals, followed by periodic evaluations to maintain results.
Research data on PRP and PRP combined with HA varies regarding the number of sessions, intervals, and formulations used. Therefore, there is currently no single universal protocol that suits everyone.
You should inform the doctor if you have any of the following conditions:
The doctor will determine whether you can proceed with the treatment or if it should be postponed.
The Non-Crosslinked HA in DuoMatrix™ is not designed to add volume or contour the face like Crosslinked HA fillers. Its primary goal is to enhance hydration and improve overall skin quality.
Individuals seeking to correct deep folds, augment the chin, enhance lips, or reshape facial contours may require other treatments based on a doctor’s assessment.
The DuoMatrix™ program focuses on skin quality rejuvenation. It is not a primary treatment for melasma, deep acne scars, or fibrotic scars. For individuals with these conditions, a doctor may consider combining it with other treatments. Such as lasers, Microneedling RF, subcision, or medications, chosen based on the type and severity of the condition.
Even though patients may have similar skin concerns, the underlying causes and skin structures can differ. An assessment allows the doctor to determine whether
Nititham Clinic provides services at both Phitsanulok and Bangkok (Silom) branches. It is supervised by Dr. Nititham Rattakasikorn (Medical License No. 37602), who has over 10 years of experience in dermatology and lasers. He is an international speaker and personally oversees and provides consultations for every case, using products and medical supplies approved by the US-FDA, Europe FDA, and Thai FDA.
Every DuoMatrix™ case begins with a thorough skin assessment before planning the treatment. This ensures that the selection and amount of PRP and Non-Crosslinked HA are specifically tailored to each individual’s skin concerns and structure.